Oestrogel is a transdermal hormone replacement therapy (HRT) that delivers estradiol, a form of oestrogen, through the skin. It is used to manage symptoms of menopause, including hot flushes, night sweats, mood changes, and vaginal dryness, which occur due to falling oestrogen levels.
This gel-based format offers an alternative to oral HRT, providing direct absorption into the bloodstream and avoiding first-pass metabolism by the liver.
How It Works
Oestrogel contains estradiol hemihydrate, which mimics the natural oestrogen produced by the ovaries. After menopause, oestrogen levels decline significantly, leading to various symptoms that can affect quality of life. When applied to the skin, Oestrogel gradually releases estradiol into circulation, helping to restore hormonal balance and reduce menopausal discomfort.
The transdermal application allows for a steady release of hormone, contributing to more stable blood levels and potentially fewer side effects compared to oral HRT.
Why Choose Oestrogel
Oestrogel is a well-established and popular choice for many women undergoing hormone replacement therapy. It offers several advantages:
Non-oral administration avoids gastrointestinal side effects
Flexible dosing based on severity of symptoms
Effective relief from vasomotor symptoms (e.g. hot flushes)
Convenient and discreet once-daily application
Lower risk of blood clots compared to oral HRT in some cases
Its clear, odourless gel dries quickly and is applied to the upper arms or thighs.
Important Note
Oestrogel should be used exactly as prescribed. For women with an intact uterus, a progestogen must be added to the HRT regimen to protect against endometrial cancer. Regular reviews with a healthcare provider are essential, especially for long-term use. Always wash hands after applying and avoid skin contact with others until the gel has dried completely.
